Makes one 12- to 14-inch pizza
Preheat the oven to 350 degrees.
In a medium bowl, toss mushrooms with olive oil, salt, and pepper. Spread mushrooms in a single layer on rimmed baking sheet and roast for 10 minutes, stirring once. Remove from oven and set aside.
Place a pizza stone or invert a metal baking sheet on an oven rack and increase oven temperature to 500 degrees. (Alternatively, you can simulate a wood-burning oven by lining the oven with unfired bricks. See directions in Basic Pizza Dough recipe.)
Dust a clean work surface with flour. Roll a portion of dough out to form a 12- to 14-inch circle, about 1/8-inch to 1/4-inch thickness. Transfer dough round to a pizza peel or to the back of a large baking sheet that has been lightly coated with cornmeal.
Spoon sauce evenly over top of dough. Top with roasted mushrooms, ham, and Manchego and drizzle with truffle oil. Gently shake peel every so often to make sure pizza isn't sticking. Once topped, quickly slide dough onto hot pizza stone and bake until toppings are bubbly and crust is browned, 10 to 12 minutes.
Cut each pizza into 6 slices and serve immediately.