Combine the cornmeal, flour, baking powder, salt, hot sauce, onions, bell peppers, jalapenos, and cayenne in a large mixing bowl and mix well to break up any lumps. Stir in the eggs, buttermilk, and water, and blend well.
Heat the oil in a large heavy saucepan over medium-high heat to 360 degrees F.
In batches, drop the batter by tablespoons into the hot oil and fry until golden brown on all sides, turning with a long-handled spoon, about 2 minutes. Remove and drain on paper towels. Repeat with the remaining batter. Sprinkle with the Creole seasoning and serve hot.
Yield: 18 hush puppies